Nrf2 Gene-R8

• Source of antioxidants for the maintenance of good health.
  

Description

Nrf2 (NF-E2-related factor 2), a transcription factor in humans that is encoded by the NFE2L2 gene, regulates the expression of a set of antioxidant and detoxifying genes. In an unstressed state, Nrf2 is anchored in the cytoplasm by its specific inhibitor Keap1 (kelch-like ECH-associated protein 1). Keap1 functions as a sensor for oxidants and electrophilic xenobiotics. In the presence of any of these substances, Keap1 gives up its inhibition of Nrf2. This action stabilizes Nrf2, allowing it to accumulate in the nucleus and bind to the antioxidant response element (ARE) located in the enhancers of its target genes. Under this circumstance, Nrf2 then upregulates a variety of antioxidant enzymes and detoxifying proteins.

Dosage

Adults: Take 1 capsule daily with food or as recommended by a healthcare practitioner.

Nutritional informations

Medicinal ingredients (per capsule):

Glucoraphanin (from broccoli extract)(Brassica oleracea italica)(seed)(truebroc®) ...... 30 mg
Green tea (Camellia sinensis, Leaf) ...... 200 mg (60% Catechins, 30% Epigallocatechin 3-gallate, 6% Caffeine)
Curcumin (Curcuma longa (rhizome) - root) ...... 130 mg
Pterostilbene ...... 50 mg

Non-medicinal ingredients: Hypromellose, magnesium stearate, stearic acid, silica.

Adultes : Prendre 1 capsule par jour avec de la nourriture ou selon les recommandations d'un professionnel de la santé.