NMN

• Provides 150 mg of nicotinamide mononucleotide (NMN) per serving, which has been shown in clinical trials to increase blood levels of NAD+.
  
• NMN is the immediate precursor to NAD+ and bridges the age-related decline in NAD+ levels.
  
• NAD+ is an essential coenzyme for many pathways related to energy production, mitochondrial health, and DNA repair, and its decline is strongly associated with aging.
  
• Vegetarian capsules with clinically established dosage

Description

NMN is a bioavailable precursor of nicotinamide adenine dinucleotide (NAD+), a key coenzyme necessary for more than 500 enzymatic reactions. As many of these enzymatic reactions are linked to cellular metabolism, aging, inflammation, circadian rhythm, mitochondrial respiration, glycolysis and DNA repair, NAD+ is considered essential for health and human longevity. NAD+ is also necessary for the expression of sirtuins, enzymes with numerous cellular regulatory effects that are particularly important for inflammation, DNA repair, and energy metabolism. Much research shows that aging results in decreased expression of NAD+ and sirtuins, which leads to impaired mitochondrial function and biogenesis and increased oxidative damage, driving the aging process itself. as well as many diseases associated with aging, including cardiovascular and metabolic diseases.

Controlled clinical trials have demonstrated multiple benefits of NMN supplementation, including improved insulin sensitivity and signaling in women with impaired glucose metabolism, as well as improved aerobic capacity in women. healthy runners, reduced sleepiness, and improved sitting in older adults.6-8 To illustrate its potential to act on aging pathways by restoring NAD+ levels, NMN supplementation during 12 weeks showed a trend toward reduction in arterial stiffness, an independent age-related risk factor for cardiovascular and metabolic diseases.

Dosage

Adults: 1 capsule 2 times daily or as directed by a health care practitioner. Consult a health care practitioner for use longer than 6 weeks.

Nutritional information

Medicinal ingredients: NMN (Nicotinamide mononucleotide) 150 mg

Nonmedicinal ingredients: Vegetable capsule (carbohydrate gum cellulose, purified water), microcrystalline cellulose, vegetable grade magnesium stearate (lubricant), stearic acid, silica.

Adultes : 1 capsule 2 fois par jour ou selon les directives d'un praticien de soins de santé. Consulter un praticien de soins de santé pour une utilisation de plus de 6 semaines.