NMN
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NMN is a bioavailable precursor of nicotinamide adenine dinucleotide (NAD+), a key coenzyme necessary for more than 500 enzymatic reactions. As many of these enzymatic reactions are linked to cellular metabolism, aging, inflammation, circadian rhythm, mitochondrial respiration, glycolysis and DNA repair, NAD+ is considered essential for health and human longevity. NAD+ is also necessary for the expression of sirtuins, enzymes with numerous cellular regulatory effects that are particularly important for inflammation, DNA repair, and energy metabolism. Much research shows that aging results in decreased expression of NAD+ and sirtuins, which leads to impaired mitochondrial function and biogenesis and increased oxidative damage, driving the aging process itself. as well as many diseases associated with aging, including cardiovascular and metabolic diseases.
Controlled clinical trials have demonstrated multiple benefits of NMN supplementation, including improved insulin sensitivity and signaling in women with impaired glucose metabolism, as well as improved aerobic capacity in women. healthy runners, reduced sleepiness, and improved sitting in older adults.6-8 To illustrate its potential to act on aging pathways by restoring NAD+ levels, NMN supplementation during 12 weeks showed a trend toward reduction in arterial stiffness, an independent age-related risk factor for cardiovascular and metabolic diseases.
Adults: 1 capsule 2 times daily or as directed by a health care practitioner. Consult a health care practitioner for use longer than 6 weeks.
Medicinal ingredients: NMN (Nicotinamide mononucleotide) 150 mg
Nonmedicinal ingredients: Vegetable capsule (carbohydrate gum [cellulose], purified water), microcrystalline cellulose, vegetable grade magnesium stearate (lubricant), stearic acid, silica.
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